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Intra-aortic Balloon Pumps Do Not Reduce Infarct Size in Patients with STEMI without Cardiac Shock: the CRISP AMI trial

Hot Line III - Acute Coronary Syndromes Topics: Acute Coronary Syndromes (ACS)


Intra-aortic balloon pump counterpulsation prior to PCI in patients with ST segment elevation MI does not reduce infarct size as measured by MRI, according to results from the Counterpulsation Reduces Infarct Size Acute Myocardial Infarction (CRISP AMI) trial.

Intra-aortic balloon counterpulsation is a procedure in which a balloon inserted in the aorta is timed to inflate at the start of diastole and to deflate before the start of systole. This increases diastolic pressure, which increases coronary perfusion and oxygen delivery to the myocardium, and facilitates ejection of blood from the left ventricle. There is evidence that LV unloading before reperfusion can reduce the extent of the infarct; infarct size has been shown to predict LV function after AMI.

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