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Alzheimer’s Disease Symptoms More Subtle in People Over 80

A new study suggests that the relationship between brain shrinkage and memory loss in Alzheimer’s disease changes across the age spectrum

 

“Those who are 85 and older make up the fastest growing population in the world,” said study author Mark Bondi, PhD, with the University of California San Diego School of Medicine and VA San Diego Healthcare System. “Our study shows how age has a dramatic effect on the profile of brain atrophy and cognitive changes evident in Alzheimer’s disease.”

The study involved 105 people with Alzheimer’s disease and 125 people who were free of dementia and recruited through the Alzheimer’s Disease Neuroimaging Initiative. Participants were grouped into those who were between the ages of 60 and 75 and those age 80 years and older. All were given tests that measured language, attention and speed of processing information, executive function, and immediate and delayed ability to recall information.

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